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Cell Cycle 15(11):14621470

During ischemia, oxygen deprivation suppresses critical metabolic pathways such as those involving fatty acids, ketone bodies, branched-chain amino acids (BCAAs), and glucose oxidation, drastically reducing ATP production

Prepared solutions should be handled per your lab SOP and used within protocol-defined stability windows

Furthermore, mutations in mitochondrial and nuclear genes encoding proteins that are required for proper assembly and stability of the mitochondrial respiratory complex also lead to complex I deficiency